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Mechanism of Action & Uses of Lopimune Tablets (Lopinavir 200 mg + Ritonavir 50 mg)
Lopimune Tablets (Lopinavir 200 mg + Ritonavir 50 mg)
Lopimune Tablets are a fixed-dose combination of Lopinavir 200 mg and Ritonavir 50 mg, widely used as part of combination antiretroviral therapy (ART) for the treatment of HIV-1 infection. The combination works by suppressing viral replication and helping maintain immune function when used alongside other antiretroviral medicines.
As a trusted pharmaceutical exporter, Cordium Pharmaceuticals Pvt. Ltd. supplies high-quality Lopinavir/Ritonavir Tablets to international healthcare providers, government tenders, NGOs, distributors, and importers.
Mechanism of Action of Lopimune Tablets
Lopimune contains two HIV protease inhibitors with complementary roles:
1. Lopinavir
Lopinavir inhibits the HIV-1 protease enzyme, preventing the cleavage of viral polyproteins into functional proteins. As a result, newly produced virus particles remain immature and non-infectious, reducing viral replication.
2. Ritonavir
Ritonavir is included primarily as a pharmacokinetic booster. It strongly inhibits the CYP3A enzyme, slowing the metabolism of lopinavir and increasing its blood concentration, thereby improving antiviral effectiveness.
Medical Uses of Lopimune Tablets
Lopimune Tablets are indicated for:
HIV-1 infection treatment in adults and pediatric patients (as part of combination ART)
Reducing HIV viral load
Supporting immune system recovery
Long-term HIV disease management under physician supervision
National HIV treatment programs and institutional procurement where clinically appropriate
Important: Current HIV treatment guidelines in many countries increasingly recommend integrase inhibitor-based regimens (such as dolutegravir) as preferred first-line therapy. Lopinavir/Ritonavir remains useful in selected clinical situations based on physician judgment, treatment history, resistance patterns, or local treatment protocols.
Advantages of Lopimune Tablets
WHO-GMP quality manufacturing
Fixed-dose combination for treatment convenience
Reliable antiviral efficacy when appropriately prescribed
Suitable for institutional procurement and export markets
Available in export-ready packaging
Why Choose Cordium Pharmaceuticals Pvt. Ltd.?
Cordium Pharmaceuticals Pvt. Ltd. is committed to supplying high-quality pharmaceutical products with:
International quality standards
Competitive export pricing
Bulk supply capability
Regulatory documentation support
Timely worldwide shipments
Private Label & Third-Party Manufacturing options
Countries We Export Lopimune Tablets
Cordium Pharmaceuticals Pvt. Ltd. exports Lopinavir/Ritonavir Tablets to:
π°πͺ Kenya
π³π¬ Nigeria
π¬π Ghana
π΅π Philippines
π»π³ Vietnam
π¦πͺ UAE
πΈπ¦ Saudi Arabia
πΊπΏ Uzbekistan
π°πΏ Kazakhstan
πΊπΈ USA*
π¬π§ UK*
πΏπ¦ South Africa
*Subject to country-specific regulatory approvals and import requirements.