Eplerenone 25 mg Tablets are prescription medicines containing eplerenone, a selective aldosterone antagonist used in cardiovascular care. Eplerenone is indicated for improving survival in stable adults with symptomatic heart failure with reduced ejection fraction (HFrEF) following an acute myocardial infarction and for the treatment of hypertension in adults.
Eplerenone 25 mg Tablets Uses
Eplerenone works by blocking the action of aldosterone, a hormone involved in sodium and water retention and cardiovascular regulation. According to current U.S. prescribing information, eplerenone is used for:
- Heart failure with reduced ejection fraction after myocardial infarction
- Hypertension (high blood pressure) in adults
For post-myocardial-infarction HFrEF, the U.S. label specifies an initial dose of 25 mg once daily, with titration to 50 mg once daily as tolerated and according to potassium levels. The appropriate dose depends on the patient's clinical condition and laboratory results.
Eplerenone 25 mg Strength and Pharmaceutical Information
Each Eplerenone 25 mg tablet contains 25 mg of eplerenone as the active pharmaceutical ingredient. Eplerenone tablets are available in 25 mg and 50 mg strengths in U.S. labeling.
The medicine is generally supplied as film-coated tablets in bottles or blister/unit-dose packaging, depending on the manufacturer and market. Packaging configurations can vary by country, manufacturer, and regulatory requirements.
Eplerenone 25 mg Storage Requirements
Proper storage helps maintain the quality and stability of the medicine. Current U.S. product labeling generally recommends storing eplerenone tablets at 25°C (77°F), with permitted excursions between 15°C and 30°C (59°F and 86°F) under controlled room-temperature conditions.
Keep tablets in their original, properly closed packaging and protect the product from unsuitable environmental conditions. Packaging should be checked for damage before use.
Important Pharmaceutical Information
Eplerenone treatment requires appropriate medical supervision because hyperkalemia (high blood potassium) is an important safety consideration. Serum potassium should be measured before starting treatment and periodically during therapy. Patients with impaired renal function or certain concomitant medicines may have increased risk.
Eplerenone also has clinically important drug-interaction and contraindication considerations, including certain strong CYP3A inhibitors and significant renal impairment. Patients should not take potassium supplements or potassium-containing salt substitutes unless advised by their healthcare professional.
Eplerenone 25 mg Tablets for Pharmaceutical Supply
Eplerenone 25 mg Tablets are relevant to pharmaceutical distributors, hospitals, healthcare procurement organizations and licensed medicine suppliers seeking cardiovascular medicines. For international pharmaceutical trade, product availability, packaging, documentation, registration status, import requirements and permitted distribution channels vary by destination country.
Cordium Pharmaceuticals Pvt. Ltd. can provide pharmaceutical supply information for Eplerenone 25 mg Tablets from India, subject to applicable regulatory and import requirements.
Frequently Asked Questions
What is Eplerenone 25 mg used for?
It is used for specific cardiovascular indications, including HFrEF following acute myocardial infarction and hypertension in adults.
What strengths are available?
U.S. labeling lists Eplerenone tablets in 25 mg and 50 mg strengths.
How should Eplerenone 25 mg Tablets be stored?
Generally, store at 25°C, with permitted excursions from 15°C to 30°C, according to U.S. labeling.
Is Eplerenone 25 mg a prescription medicine?
Yes. Eplerenone tablets are prescription medicines and should be used under appropriate medical supervision.
Can Eplerenone affect potassium levels?
Yes. Eplerenone can increase serum potassium, making potassium monitoring an important part of treatment.
