Roflumilast Tablet – Product Overview
Generic Name: Roflumilast
Dosage Form: Tablet
Common Strength: 500 mcg
Drug Class: Selective PDE4 inhibitor
Therapeutic Category: Respiratory / COPD medicine
Primary Use: Maintenance treatment in selected patients with severe COPD
Prescription Status: Prescription medicine; local regulations apply
Roflumilast works by inhibiting PDE4, an enzyme involved in the breakdown of cyclic AMP. Increased intracellular cyclic AMP contributes to anti-inflammatory activity in the lungs.
How Does Roflumilast Work?
Roflumilast and its active metabolite inhibit PDE4, increasing intracellular cyclic AMP in lung tissue. This helps reduce inflammatory activity associated with COPD.
Unlike a rescue inhaler, roflumilast is not a bronchodilator and should not be used for immediate relief of acute bronchospasm.
Roflumilast Tablet Uses
Roflumilast is used as a maintenance treatment to help reduce the risk of COPD exacerbations in appropriately selected adults with:
Severe COPD
Chronic bronchitis
A history of COPD exacerbations
A need for additional maintenance treatment alongside appropriate bronchodilator therapy
The exact indication and approved use can vary by country and product authorization.
Advantages of Roflumilast
1. Oral maintenance treatment
Roflumilast is administered as an oral tablet, providing an alternative to adding another inhaled medicine in appropriately selected patients.
2. PDE4-targeted anti-inflammatory action
Its selective PDE4 inhibition provides a mechanism specifically targeting inflammatory pathways involved in COPD.
3. Helps reduce COPD exacerbation risk
In the approved population, roflumilast is intended to reduce the risk of COPD exacerbations.
4. Useful as add-on therapy
Roflumilast can be incorporated into an appropriate COPD maintenance regimen when prescribed by a qualified healthcare professional.
5. Global pharmaceutical sourcing opportunity
Cordium Pharmaceuticals can support enquiries from pharmacies, distributors, healthcare organizations and other eligible pharmaceutical buyers, subject to destination-country regulations.
Disadvantages, Limitations & Precautions
Roflumilast is not suitable for everyone. Important limitations include:
It is not a rescue medicine for acute breathing difficulty or acute bronchospasm.
Gastrointestinal adverse effects such as diarrhea, nausea and abdominal discomfort may occur.
Headache and insomnia may occur.
Unintentional or clinically significant weight loss can occur and should be monitored.
Psychiatric symptoms, including worsening depression, anxiety, insomnia or suicidal thoughts, require prompt medical attention.
Roflumilast is contraindicated in moderate-to-severe hepatic impairment in U.S. labeling.
Drug interactions should be reviewed by a healthcare professional.
Patients with a history of depression or suicidal behavior require careful risk-benefit assessment.
Patients should use roflumilast only according to the prescription and medical advice provided by their healthcare professional.
Roflumilast 500 mcg Dosage Information
For the U.S. labeling, the maintenance dose for COPD is 500 mcg once daily, with or without food. A 250 mcg dose may be used initially for four weeks in some prescribing approaches to improve tolerability, but 250 mcg is not the therapeutic maintenance dose.
Do not self-start, stop or change the dose without medical advice.
Roflumilast Tablet Export from India
Cordium Pharmaceuticals Pvt. Ltd. provides pharmaceutical sourcing and export support from India for international buyers, subject to product availability, documentation and the import regulations of the destination country.
Target Markets & Major Cities
Singapore
Singapore
Jurong
Tampines
Woodlands
Malaysia
Kuala Lumpur
George Town
Johor Bahru
Shah Alam
Petaling Jaya
Kenya
Nairobi
Mombasa
Kisumu
Nakuru
USA
New York City
Los Angeles
Chicago
Houston
Miami
Dallas
UK
London
Birmingham
Manchester
Glasgow
Liverpool
UAE
Dubai
Abu Dhabi
Sharjah
Ajman
Al Ain
South Africa
Johannesburg
Cape Town
Durban
Pretoria
Port Elizabeth / Gqeberha
Why Choose Cordium Pharmaceuticals?
Reliable Pharmaceutical Export Support
Cordium Pharmaceuticals Pvt. Ltd. is positioned to support international pharmaceutical sourcing enquiries from India.
Roflumilast Tablet Enquiry – Cordium Pharmaceuticals
Company: Cordium Pharmaceuticals Pvt. Ltd.
WhatsApp: +91-9405117673
Email: info@cordiumpharma.com
Generic Name: Roflumilast
Dosage Form: Tablet
Common Strength: 500 mcg
Drug Class: Selective PDE4 inhibitor
Therapeutic Category: Respiratory / COPD medicine
Primary Use: Maintenance treatment in selected patients with severe COPD
Prescription Status: Prescription medicine; local regulations apply
Roflumilast works by inhibiting PDE4, an enzyme involved in the breakdown of cyclic AMP. Increased intracellular cyclic AMP contributes to anti-inflammatory activity in the lungs.
How Does Roflumilast Work?
Roflumilast and its active metabolite inhibit PDE4, increasing intracellular cyclic AMP in lung tissue. This helps reduce inflammatory activity associated with COPD.
Unlike a rescue inhaler, roflumilast is not a bronchodilator and should not be used for immediate relief of acute bronchospasm.
Roflumilast Tablet Uses
Roflumilast is used as a maintenance treatment to help reduce the risk of COPD exacerbations in appropriately selected adults with:
Severe COPD
Chronic bronchitis
A history of COPD exacerbations
A need for additional maintenance treatment alongside appropriate bronchodilator therapy
The exact indication and approved use can vary by country and product authorization.
Advantages of Roflumilast
1. Oral maintenance treatment
Roflumilast is administered as an oral tablet, providing an alternative to adding another inhaled medicine in appropriately selected patients.
2. PDE4-targeted anti-inflammatory action
Its selective PDE4 inhibition provides a mechanism specifically targeting inflammatory pathways involved in COPD.
3. Helps reduce COPD exacerbation risk
In the approved population, roflumilast is intended to reduce the risk of COPD exacerbations.
4. Useful as add-on therapy
Roflumilast can be incorporated into an appropriate COPD maintenance regimen when prescribed by a qualified healthcare professional.
5. Global pharmaceutical sourcing opportunity
Cordium Pharmaceuticals can support enquiries from pharmacies, distributors, healthcare organizations and other eligible pharmaceutical buyers, subject to destination-country regulations.
Disadvantages, Limitations & Precautions
Roflumilast is not suitable for everyone. Important limitations include:
It is not a rescue medicine for acute breathing difficulty or acute bronchospasm.
Gastrointestinal adverse effects such as diarrhea, nausea and abdominal discomfort may occur.
Headache and insomnia may occur.
Unintentional or clinically significant weight loss can occur and should be monitored.
Psychiatric symptoms, including worsening depression, anxiety, insomnia or suicidal thoughts, require prompt medical attention.
Roflumilast is contraindicated in moderate-to-severe hepatic impairment in U.S. labeling.
Drug interactions should be reviewed by a healthcare professional.
Patients with a history of depression or suicidal behavior require careful risk-benefit assessment.
Patients should use roflumilast only according to the prescription and medical advice provided by their healthcare professional.
Roflumilast 500 mcg Dosage Information
For the U.S. labeling, the maintenance dose for COPD is 500 mcg once daily, with or without food. A 250 mcg dose may be used initially for four weeks in some prescribing approaches to improve tolerability, but 250 mcg is not the therapeutic maintenance dose.
Do not self-start, stop or change the dose without medical advice.
Roflumilast Tablet Export from India
Cordium Pharmaceuticals Pvt. Ltd. provides pharmaceutical sourcing and export support from India for international buyers, subject to product availability, documentation and the import regulations of the destination country.
Target Markets & Major Cities
Singapore
Singapore
Jurong
Tampines
Woodlands
Malaysia
Kuala Lumpur
George Town
Johor Bahru
Shah Alam
Petaling Jaya
Kenya
Nairobi
Mombasa
Kisumu
Nakuru
USA
New York City
Los Angeles
Chicago
Houston
Miami
Dallas
UK
London
Birmingham
Manchester
Glasgow
Liverpool
UAE
Dubai
Abu Dhabi
Sharjah
Ajman
Al Ain
South Africa
Johannesburg
Cape Town
Durban
Pretoria
Port Elizabeth / Gqeberha
Why Choose Cordium Pharmaceuticals?
Reliable Pharmaceutical Export Support
Cordium Pharmaceuticals Pvt. Ltd. is positioned to support international pharmaceutical sourcing enquiries from India.
Roflumilast Tablet Enquiry – Cordium Pharmaceuticals
Company: Cordium Pharmaceuticals Pvt. Ltd.
WhatsApp: +91-9405117673
Email: info@cordiumpharma.com
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