Avanafil 50 mg tablets are an oral prescription medicine containing avanafil, a phosphodiesterase type-5 (PDE5) inhibitor used for the treatment of erectile dysfunction (ED) in adult men. Avanafil works by supporting increased blood flow to the penis during sexual stimulation, helping achieve and maintain an erection.
For pharmaceutical importers, distributors and other licensed healthcare-sector buyers in South Africa, understanding the product, strength, documentation and applicable regulatory requirements is important when sourcing Avanafil 50 mg tablets from India.
What Is Avanafil 50 mg?
Avanafil 50 mg contains 50 mg of avanafil as the active pharmaceutical ingredient (API). It belongs to the PDE5 inhibitor class of medicines.
PDE5 inhibitors work by increasing the effects of nitric oxide–mediated signalling involved in penile blood flow. Avanafil does not itself cause an erection; sexual stimulation is required for the medicine to produce its intended effect.
Avanafil is available in multiple strengths in some markets, including 50 mg, 100 mg and 200 mg tablets. The 50 mg strength may be used when a lower dose is appropriate based on individual response, tolerability or certain concomitant medicines.
Avanafil 50 mg Uses
The primary therapeutic use of avanafil is the treatment of erectile dysfunction in adult males. It is not intended to increase sexual desire and should be used according to the prescribing information and advice of a qualified healthcare professional.
For South African buyers, product specifications, approved indications, labelling and regulatory status should be verified for the specific product being sourced before commercial distribution.
How Does Avanafil Work?
Avanafil is a PDE5 inhibitor. During sexual stimulation, nitric oxide signalling contributes to the production of cyclic guanosine monophosphate (cGMP), which helps relax smooth muscle and increase blood flow in penile tissue. Avanafil inhibits PDE5, helping maintain cGMP activity and supporting the erectile response.
Avanafil 50 mg Dosage Information
The appropriate dose should be determined by a healthcare professional. In the U.S. prescribing information for avanafil, the standard starting dose is 100 mg taken as needed; the dose may be reduced to 50 mg, with the 50 mg dose specified at approximately 30 minutes before sexual activity. The maximum recommended frequency is once daily.
The dosage may differ according to the patient's medical condition, other medicines being taken and applicable local prescribing information. Avanafil should not be used as a self-prescribed treatment.
Important Safety Information
Avanafil has important contraindications and drug interactions. In particular, it should not be used with organic nitrates, because the combination can cause a potentially dangerous drop in blood pressure. It is also contraindicated with certain guanylate cyclase stimulators. Strong CYP3A4 inhibitors should not be used with avanafil, while moderate CYP3A4 inhibitors require specific dose limitations.
Common adverse reactions reported with avanafil include headache, flushing, nasal congestion, nasopharyngitis and back pain. An erection lasting longer than four hours requires emergency medical attention. Sudden vision or hearing changes also require prompt medical evaluation.
Avanafil 50 mg Supply for South Africa
South African pharmaceutical buyers considering Avanafil 50 mg tablets from India should verify the supplier's product documentation, manufacturing details, batch information, packaging specifications, quality documents and shipping requirements.
Importation and distribution of medicines in South Africa are regulated by the South African Health Products Regulatory Authority (SAHPRA). SAHPRA provides specific processes for the importation of medical products and licensing of pharmaceutical establishments.
The applicable regulatory status of the specific Avanafil product should be confirmed before importing or distributing it. SAHPRA states that medicines generally require registration before they may be sold or marketed, with specific authorisation mechanisms applying in certain circumstances.
Why Source Avanafil 50 mg from India?
India is an established pharmaceutical manufacturing and export market, making Indian suppliers a potential sourcing option for international pharmaceutical buyers. Global Pharma Trade can assist eligible South African buyers with Avanafil 50 mg tablet supply from India, subject to product availability, applicable documentation and South African regulatory requirements.
Buyers can request information about product specifications, packaging, quantity requirements, export documentation and quotation for their pharmaceutical sourcing needs.
Frequently Asked Questions
What is Avanafil 50 mg used for?
Avanafil 50 mg is used for the treatment of erectile dysfunction in adult men.
Is Avanafil 50 mg a prescription medicine?
Avanafil is a prescription medicine in the referenced U.S. labeling, and South African buyers should follow applicable South African prescribing and regulatory requirements.
Can Avanafil 50 mg be imported into South Africa?
Medicine imports are subject to South African regulatory controls. Buyers should verify the specific product's registration or applicable authorisation and import requirements with SAHPRA before ordering.
Can South African pharmaceutical distributors request bulk quotations?
Licensed and eligible pharmaceutical buyers can contact Global Pharma Trade to enquire about product availability, quantities, documentation and export supply from India, subject to applicable regulatory requirements.
Request an Avanafil 50 mg Supply Quote
Looking for Avanafil 50 mg tablets from India for the South African pharmaceutical market? Contact Global Pharma Trade with your required quantity and destination details to discuss product availability, specifications, documentation and a quotation.