Irinotecan Injection 40mg/100mg – Uses, Dosage, Benefits & Side Effects
Description
Overview
Irinotecan Injection 40mg/100mg is a prescription chemotherapy medicine containing irinotecan hydrochloride. It belongs to the topoisomerase I inhibitor class and is mainly used in chemotherapy regimens for colorectal cancer. It is administered intravenously by qualified healthcare professionals.
Uses
Irinotecan Injection may be used for:
Metastatic colorectal cancer
Advanced colorectal cancer
Previously treated colorectal cancer
Combination chemotherapy regimens with other anticancer medicines
The exact use depends on the patient's cancer type and the oncologist's treatment protocol.
Benefits
Helps slow the growth of certain cancer cells
Used in established colorectal cancer chemotherapy regimens
Can be combined with other anticancer medicines
Provides systemic treatment for advanced cancer
How It Works
Irinotecan blocks topoisomerase I, an enzyme needed for cancer-cell DNA replication. This causes DNA damage and can lead to the death of rapidly dividing cancer cells.
Dosage & Administration
Irinotecan dosage is individualized according to the patient's body surface area, cancer type, treatment regimen, blood counts, liver function, and previous treatment.
It is administered as an IV infusion, commonly over approximately 90 minutes depending on the prescribed regimen.
Do not self-administer or change the dose. The treating oncologist determines the appropriate dose and schedule.
Side Effects
Common side effects include:
Diarrhea
Nausea and vomiting
Abdominal cramps
Fatigue and weakness
Loss of appetite
Anemia
Neutropenia
Fever or infection
Mouth sores
Hair loss
Important Safety Information
Severe diarrhea and reduced white blood-cell counts can occur with irinotecan. Patients should promptly contact their healthcare provider for severe diarrhea, fever, signs of infection, dehydration, unusual bleeding, or severe weakness.
Precautions
Tell your doctor if you have:
Liver problems
Previous chemotherapy or radiation
Low blood-cell counts
A history of severe diarrhea
Drug allergies
Pregnancy or plans for pregnancy
Other medicines you are taking
Regular blood tests may be required during treatment.
FAQs
What is Irinotecan Injection used for?
It is a chemotherapy medicine primarily used in selected treatment regimens for colorectal cancer.
What strengths are available?
Common presentations include 40mg/2mL and 100mg/5mL vials.
How is Irinotecan administered?
It is given by intravenous infusion under professional medical supervision.
Does Irinotecan cause diarrhea?
Yes. Diarrhea is a common and potentially serious side effect. Severe diarrhea requires prompt medical attention.
Can Irinotecan lower white blood cells?
Yes. It can cause neutropenia and other blood-cell abnormalities, so blood counts should be monitored.
Can Irinotecan cause hair loss?
Yes, hair loss may occur during treatment.
Who should determine the Irinotecan dose?
The treating oncologist should determine the dose based on the patient's condition and chemotherapy protocol.
Product Information
Feature Details
Product Irinotecan Injection
Strength 40mg / 100mg
Active Ingredient Irinotecan Hydrochloride
Route Intravenous
Class Antineoplastic chemotherapy
Main Use Colorectal cancer treatment
Medical Disclaimer: Irinotecan is a prescription chemotherapy medicine and should only be used under qualified medical supervision. This information is for educational purposes and does not replace professional medical advice.
