Perjeta 420 mg Injection (Pertuzumab): Uses, Benefits, Side Effects and Product Information

Perjeta 420mg Injection is a prescription oncology medicine containing pertuzumab, a monoclonal antibody used in specific treatment regimens for HER2-positive breast cancer. It targets the human epidermal growth factor receptor 2 (HER2), a protein that can promote the growth of certain breast cancer cells.

Perjeta is supplied as a concentrate for intravenous infusion, commonly in a 420mg/14mL vial. It is administered by qualified healthcare professionals in a clinical setting. Treatment suitability depends on the cancer stage, HER2 test results, previous treatment and the patient's overall health.

Cordium Pharmaceuticals Pvt Ltd provides pharmaceutical product information to help healthcare professionals and eligible pharmaceutical trade partners understand relevant product specifications. Availability, supply and applicable regulatory requirements should be confirmed for the destination market.

Perjeta 420mg Injection Uses

Perjeta is used in combination with other medicines for certain patients with HER2-positive breast cancer. Depending on the approved indication in the relevant country, treatment may include:

HER2-positive metastatic breast cancer: For eligible adults whose cancer has spread or is locally recurrent and cannot be removed surgically.

Early-stage HER2-positive breast cancer: In selected patients, as part of a treatment regimen before surgery and, where indicated, after surgery to reduce the risk of recurrence.

The exact indication and combination therapy vary according to the patient's clinical circumstances and local prescribing information. HER2 status must be established using an appropriate diagnostic test.

Benefits of Perjeta 420mg Injection

Perjeta offers potential clinical benefits when prescribed for an approved indication and used as part of a specialist-directed treatment plan.

Targeted treatment: Pertuzumab binds to HER2 and interferes with receptor signalling involved in cancer cell growth.

Combination therapy: It can be used alongside trastuzumab and chemotherapy in specified treatment regimens.

Potential disease control: In eligible patients, combination treatment may improve clinical outcomes, depending on the disease setting and individual response.

Specialist-supervised care: Its use within an oncology treatment plan allows healthcare professionals to monitor response and manage adverse effects.

Individual outcomes vary. Perjeta is not suitable for every breast cancer patient and should not be considered a guaranteed cure.

Perjeta 420mg Injection Side Effects

Possible side effects depend on the treatment combination, dose schedule and individual health status. Commonly reported adverse effects include:

Diarrhoea, nausea and vomiting

Fatigue and weakness

Hair loss

Skin rash

Reduced appetite

Infusion-related reactions

Important safety information: Perjeta can cause serious heart problems, including reduced heart function, and severe infusion-related or allergic reactions. It may also cause harm to an unborn baby. Patients should inform their oncologist about existing heart conditions, pregnancy or plans to become pregnant.

Seek urgent medical attention for breathing difficulties, facial or throat swelling, severe dizziness or other signs of a serious reaction. Heart function should be assessed and monitored as directed by the treating specialist.

Frequently Asked Questions (FAQs)

1. What is Perjeta 420mg Injection used for?

It is used with other medicines to treat specific types and stages of HER2-positive breast cancer, according to approved prescribing information.

2. What is the active ingredient in Perjeta?

The active ingredient is pertuzumab, a HER2-targeted monoclonal antibody.

3. How is Perjeta 420mg Injection administered?

It is given as an intravenous infusion by trained healthcare professionals. The dose and schedule are determined by the treating oncologist.

4. Is Perjeta chemotherapy?

No. Perjeta is a targeted monoclonal antibody, although it may be prescribed alongside chemotherapy and other targeted medicines.

5. Where can healthcare professionals find Perjeta product information?

Healthcare professionals and eligible pharmaceutical buyers can contact Cordium Pharmaceuticals Pvt Ltd to enquire about product details, availability and applicable market-specific regulatory documentation.

Contact Cordium Pharmaceuticals Pvt Ltd

For enquiries regarding Perjeta 420mg Injection product information and pharmaceutical supply, contact Cordium Pharmaceuticals Pvt Ltd through its official business channels. All supply is subject to applicable laws, product authorization and destination-country requirements.

Medical disclaimer: This page is for general informational purposes only and does not replace the approved product label or advice from a qualified healthcare professional. Perjeta is a prescription medicine and must be used under specialist supervision.