ISENTRESS 400 mg Tablets in Singapore – Product Information

ISENTRESS 400 mg Tablets contain raltegravir, an antiretroviral medicine used in combination with other HIV medicines to manage HIV-1 infection. Patients, healthcare professionals, and pharmaceutical procurement teams in Singapore can use this page to understand the product’s composition, strength, therapeutic use, safety information, and purchasing considerations.

ISENTRESS 400 mg Tablets – Product Description

ISENTRESS is a prescription medicine belonging to the integrase strand transfer inhibitor (INSTI) class of antiretroviral drugs. It works by blocking HIV integrase, an enzyme the virus needs to insert its genetic material into human cells. This helps reduce viral replication when the medicine is used as part of an appropriate antiretroviral treatment regimen.

The product is intended for use under medical supervision. Treatment selection depends on the patient's clinical condition, previous HIV treatment, resistance profile, and other prescribed medicines.

Product Specifications and Strength

Brand name: ISENTRESS

Active ingredient: Raltegravir

Salt form: Raltegravir potassium

Strength: 400 mg raltegravir per tablet

Dosage form: Film-coated tablet

Route of administration: Oral

Therapeutic category: Antiretroviral medicine

Prescription status in Singapore: Prescription-only medicine

Each tablet contains 434.4 mg of raltegravir potassium, equivalent to 400 mg of raltegravir. The Singapore National Drug Formulary lists ISENTRESS 400 mg Tablets under registration number SIN13568P. Always verify the current registration and product details before procurement.

Uses and Potential Benefits of ISENTRESS

ISENTRESS is indicated for the treatment of HIV-1 infection in combination with other antiretroviral medicines, according to the applicable prescribing information.

Potential treatment benefits include:

HIV replication control: Raltegravir blocks an essential step in the HIV replication cycle.

Viral load reduction: When combined with an effective treatment regimen, it can help lower the amount of HIV in the blood.

Immune system support: Effective HIV treatment can help preserve or improve immune function.

Combination treatment options: It may be incorporated into an appropriate antiretroviral regimen selected by a qualified healthcare professional.

Individual treatment outcomes vary. ISENTRESS is not a cure for HIV and should not be used alone unless specifically directed by the applicable clinical protocol.

Dosage and Administration

The appropriate dose depends on the prescribed treatment regimen and patient-specific factors. The 400 mg film-coated tablet is commonly prescribed twice daily for adults under applicable dosing guidance, but patients must follow their own prescription.

ISENTRESS may be taken with or without food. Do not stop treatment, change the dose, or substitute another formulation without consulting a healthcare professional. Certain antacids containing aluminium or magnesium can interact with raltegravir, so medication and supplement use should be reviewed by a pharmacist or doctor.

Side Effects and Safety Precautions

Possible side effects include:

Nausea and diarrhoea

Headache and dizziness

Fatigue

Sleep disturbances

Muscle pain

Seek urgent medical attention for a severe rash, facial swelling, breathing difficulties, or symptoms suggesting a serious allergic reaction. Severe muscle pain, weakness, or dark urine also requires prompt medical assessment because rare serious muscle complications can occur.

Tell your doctor about existing medical conditions, allergies, and all medicines or supplements you take. Never discontinue HIV treatment without medical advice.

Buying ISENTRESS 400 mg Tablets in Singapore

People searching online for ISENTRESS 400 mg Tablets should verify the product's authenticity, registration status, packaging, expiry date, and authorised supply channel. In Singapore, prescription-only medicines must be obtained through legally permitted channels and with the required prescription.

Healthcare institutions and pharmaceutical procurement teams should confirm supplier authorisation, product documentation, storage requirements, and availability before placing an order. Availability and pricing may vary by supplier.

Frequently Asked Questions (FAQs)

1. What is the active ingredient in ISENTRESS 400 mg Tablets?

The active ingredient is raltegravir, supplied as raltegravir potassium. Each tablet provides 400 mg of raltegravir.

2. What is ISENTRESS 400 mg used for?

It is used with other antiretroviral medicines to treat HIV-1 infection.

3. Is ISENTRESS available in Singapore?

The Singapore National Drug Formulary lists ISENTRESS 400 mg Tablets as a registered prescription-only medicine. Confirm current registration and availability before purchase.

4. Can I take ISENTRESS without other HIV medicines?

It is generally prescribed as part of a combination antiretroviral regimen. Follow your HIV specialist's instructions.